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  • Asian Journal of Immunology

DNA Bends the Knee to Transcription Factors

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During gene expression, multiprotein-DNA complexes are formed to regulate transcription. Binding of transcription factors can locally deform DNA, for example, by bending its helical axis. Dimers or oligomers of transcription factors may interact with DNA at multiple sites and determine the bending angle collectively.

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Hybrid human–chicken embryos illuminate key developmental milestone

Coloured scanning electron micrograph of human embryonic stem cells

A new technique reveals the earliest stages of human development without the need for human embryos.

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Inherent feminizing effect of germ cells: New insights into sex determination

Identification of cells that determine the female gender in teleost fish (medaka). The pink circles represent germ cells (the common origin of sperm and eggs). Germ cells, irrespective of the sexual fate (to become sperm or eggs), have the potential to feminize the body in medaka. The pink arrows indicate the feminizing effect from germ cell.

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Over 30,000 Published Studies Could Be Wrong Due to Contaminated Cells

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Researchers warn that large parts of biomedical science could be invalid due to a cascading history of flawed data in a systemic failure going back decades.

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List of Best Open Access Pediatric Journal

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Top 20 Open Access Cardiology Journal

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Sex after 65: Poll finds links to health, gender differences, lack of communication

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Majority are satisfied with their sex lives; nearly 1 in 5 older men use medications or supplements, U-M/AARP National Poll on Healthy Aging finds

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Top 50 Open Access Mathematics Journal

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The Secret to Sperm’s Sexy Swimming

Human sperm cells get an extra oomph forward as they swim, thanks to interconnected elastic springs in their tails that communicate with other regions of the tail, a new study finds. These elastic springs transmit mechanical information to the distant parts of the tail, helping it bend as it wriggles its way toward an egg, the researchers said.

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Gut Microbes Could Play a Role in Heart Disease Too

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Research has shown that having the right gut microbes can reduce the risk of heart disease – if you’re a mouse. Now, our latest study, published in the European Heart Journal, shows that this might be true for humans, too.

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Australian budget delivers for science facilities and medical research

The Australian Synchrotron Project

Research facilities and medicine were among the winners for science in Australia’s 2018–19 national budget, which was proposed on Tuesday.

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Top 50 Open Access Physical Science Journal

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Top Open Access Computer Science Journal

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