Caterpillar wrestling, next-generation CRISPR, and the troubled James Webb Space Telescope

(LEFT TO RIGHT): SHINJI SUGIURA; KC ROEYER/UNIVERSITY OF CALIFORNIA, BERKELEY; NASA/DESIREE STOVER/FLICKR (CC BY-NC-ND 2.0)

Thirteen million degrees of Kevin Bacon: World’s largest family tree shines light on life span, who marries whom

Researchers have published what may be the largest family tree ever: a genealogy database stretching back 5 centuries that links 13 million people related by blood or marriage. The tree has already illuminated links between longevity and certain genes, and it has provided insight into why some of our ancestors married whom they did. And researchers say that’s just a start.

Upgrade makes genome editor CRISPR more muscular, precise

You wouldn’t know it from the excitement generated by the revolutionary genome editing method known as CRISPR, but as practiced, it is far from perfect. Its standard components can find and cut DNA in only a limited fraction of the genome, and its molecular scissors are wobbly, leading to “off-target” mutations. Now, a team led by chemist David Liu at Harvard University has engineered a version of CRISPR that potentially is both more dexterous and more precise.

The science of resilience: What are the ingredients that help people cope?

Resilience is on many people’s minds these days. Hurricanes and fires regularly wallop communities, the risks of climate change loom large, and the horrors of war and the refugee crises it spawns show no signs of abating. It’s an unsettling time—made more so because we humans feel unable to control many of these human-influenced events. But even though hardship cripples some, others rebound. What can science teach us about how we might gird for future challenges and adapt to them? A package of stories in this week’s issue of Science explores what scientists are learning about resilience in a challenging world.

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