News Update on Gastroenterology: Feb:2020

American College of Gastroenterology Guidelines for Colorectal Cancer Screening 2008

This document is the first update of the American College of Gastroenterology (ACG) colorectal cancer (CRC) screening recommendations since 2000. The CRC screening tests are now grouped into cancer prevention tests and cancer detection tests. Colonoscopy every 10 years, beginning at age 50, remains the preferred CRC screening strategy. It is recognized that colonoscopy is not available in every clinical setting because of economic limitations. It is also realized that not all eligible persons are willing to undergo colonoscopy for screening purposes. In these cases, patients should be offered an alternative CRC prevention test (flexible sigmoidoscopy every 5-10 years, or a computed tomography (CT) colonography every 5 years) or a cancer detection test (fecal immunochemical test for blood, FIT). [1]

European Society for Pediatric Gastroenterology, Hepatology, and Nutrition Guidelines for the Diagnosis of  Coeliac Disease

Objective: Diagnostic criteria for coeliac disease (CD) from the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) were published in 1990. Since then, the autoantigen in CD, tissue transglutaminase, has been identified; the perception of CD has changed from that of a rather uncommon enteropathy to a common multiorgan disease strongly dependent on the haplotypes human leukocyte antigen (HLA)-DQ2 and HLA-DQ8; and CD-specific antibody tests have improved. [2]

ORGANIC AND FUNCTIONAL DISORDERS IN 2000 GASTROENTEROLOGY OUTPATIENTS

To determine the relative frequency of different diseases and of functional gastrointestinal disorders among patients referred by general practitioners to a gastroenterology clinic, 2000 patients referred over a five-year period were studied. 980 had organic diseases, of which peptic ulcer, oesophagitis, and inflammatory bowel disease accounted for about half. 888 patients had functional disorders of the gastrointestinal tract, without any disease. [3]

A Case-control Study on the Risk of Upper Gastrointestinal Bleeding in Patients Taking Non-steroidal Anti-inflammataory Drugs (NSAIDs) in Mashhad, Iran

Introduction: Gastrointestinal bleeding is one of the most common causes of patient admissions at emergency wards. Despite considering nonsteroidal antiinflammatory drugs (NSAIDs), aspirin and Helicobacter pylori as the leading causes, mortality from gastrointestinal (GI) bleeding is still high. So pattern of NSAID consumption and related conditions may help in preventative behavior. [4]

Massive Hematemesis from Gastric Dieulafoy’s Lesion, Surgery as a Curative Option When There is Lack of Access to Expertise

Dieulafoy’s lesion is an acute GI (gastrointestinal) bleeding disorder, a rare but life-threatening condition due to recurrent bleeding. The affected arteriole can protrude through a small defect in the mucosa, becomes susceptible to the mechanical trauma even of a minor level and gradually erodes into the lumen to cause severe acute GI bleeding. [5]

Reference

[1 ] Rex, D.K., Johnson, D.A., Anderson, J.C., Schoenfeld, P.S., Burke, C.A. and Inadomi, J.M., 2009. American College of Gastroenterology guidelines for colorectal cancer screening 2008. American Journal of Gastroenterology104(3), pp.739-750.

[2 ] Husby, S., Koletzko, S., Korponay-Szabó, I.R., Mearin, M.L., Phillips, A., Shamir, R., Troncone, R., Giersiepen, K., Branski, D., Catassi, C. and Lelgeman, M., 2012. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition guidelines for the diagnosis of coeliac disease. Journal of pediatric gastroenterology and nutrition54(1), pp.136-160.

[3] Harvey, R., Salih, S.Y. and Read, A., 1983. Organic and functional disorders in 2000 gastroenterology outpatients. The Lancet321(8325), pp.632-634.

[4]  Samaneh, S., Zhila, T., Saeid, E., Elham, M., Ali, K., Faroughi, F. and Mitra, A. (2019) “A Case-control Study on the Risk of Upper Gastrointestinal Bleeding in Patients Taking Non-steroidal Anti-inflammataory Drugs (NSAIDs) in Mashhad, Iran”, Asian Journal of Research and Reports in Gastroenterology, 1(1), pp. 1-9. Available at:http://www.journalajrrga.com/index.php/AJRRGA/article/view/30091 (Accessed: 25February2020).

[5]  Zarak, M. S., Kakar, A., Sana, H., Haq, N. U., Nasim, A., Baloch, S. A. and Tareen, H. K. (2018) “Massive Hematemesis from Gastric Dieulafoy’s Lesion, Surgery as a Curative Option When There is Lack of Access to Expertise”, Asian Journal of Research and Reports in Gastroenterology, 1(1), pp. 1-5. Available at: http://www.journalajrrga.com/index.php/AJRRGA/article/view/25417 (Accessed: 25February2020).

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