News Update on Staphylococcus: March – 2020

Staphylococcus aureus Infections

Micrococcus, which, when limited in its extent and activity, causes acute suppurative inflammation (phlegmon), produces, when more extensive and intense in its action on the human system, the most virulent forms of septicæmia and pyæmia. [1]

Surface protein adhesins of Staphylococcus aureus

Staphylococcus aureus can colonize the host to initiate infection by adhering to components of the extracellular matrix. Adherence is mediated by surface protein adhesins (MSCRAMMs). Ligand binding by these fibronectin-, fibrinogen- and collagen-binding proteins occurs by distinct mechanisms that are being investigated at the molecular level. [2]

Intranasal Mupirocin to Prevent Postoperative Staphylococcus aureus Infections

Patients with nasal carriage of Staphylococcus aureus have an increased risk of surgical-site infections caused by that organism. Treatment with mupirocin ointment can reduce the rate of nasal carriage and may prevent postoperative S. aureus infections. [3]

Comparative Studies on Effectiveness of Branded and Unbranded Disinfectants on E. coli and Staphylococcus Species

Aims: To compare the antimicrobial potential of branded and unbranded disinfectants on clinical bacterial isolates.

Study Design: The agar-well diffusion and micro broth dilution were adopted for the study. Ten disinfectants of which five were branded (industrial prepared) and five unbranded (indigenous prepared) were used against E. coli and Staphylococcus aureus. [4]

Prevalence of Methicillin-resistant Staphylococcus aureus in Abeokuta, Nigeria

This study examined the prevalence of Methicillin-resistant Staphylococcus aureus (MRSA) in clinical samples of patients in Abeokuta, Ogun State, Nigeria using standard recommended procedures [5]


[1] Lowy, F.D., 1998. Staphylococcus aureus infections. New England journal of medicine339(8), pp.520-532.

[2] Foster, T.J. and Höök, M., 1998. Surface protein adhesins of Staphylococcus aureus. Trends in microbiology6(12), pp.484-488.

[3]Perl, T.M., Cullen, J.J., Wenzel, R.P., Zimmerman, M.B., Pfaller, M.A., Sheppard, D., Twombley, J., French, P.P., Herwaldt, L.A. and Mupirocin and the Risk of Staphylococcus aureus Study Team, 2002. Intranasal mupirocin to prevent postoperative Staphylococcus aureus infections. New England Journal of Medicine346(24), pp.1871-1877.

[4] Akani, N. P., Williams, J. O. and Nnamdi, A. U. (2019) “Comparative Studies on Effectiveness of Branded and Unbranded Disinfectants on E. coli and Staphylococcus Species”, South Asian Journal of Research in Microbiology, 2(4), pp. 1-8. doi: 10.9734/sajrm/2018/v2i430071.

[5] A. Osinupebi, O., A. Osiyemi, J., M. Deji-Agboola, A., A. Akinduti, P., Ejilude, O., O. Makanjuola, S., O. Sunmola, N. and O. Osiyemi, E. (2018) “Prevalence of Methicillin-resistant Staphylococcus aureus in Abeokuta, Nigeria”, South Asian Journal of Research in Microbiology, 1(1), pp. 1-8. doi: 10.9734/sajrm/2018/v1i1718.

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