Assessment of Rhesus D Distribution in Blood Group of Individuals and the Relationship with Bleeding Time

In randomly selected subjects from Niger Delta University, Bayelsa State, Nigeria, the relationship between rhesus factor and bleeding time in blood group O was investigated using standard antisera and Duke’s system. The O+ group had a shorter bleeding time (1.32 ± 0.41 min) than the O- group (1.33 ± 0.37 min). Gender-wise, females in the O+ group had shorter bleeding times (1.30 ± 0.40 min) than males in the O+ group (1.34 ± 0.42 min), and males in the O- blood group had shorter bleeding times (1.20 ± 0.39 min) than females in the O- group (1.39 ± 0.37 min). The same gender comparison reveals that males in the O+ group had a longer bleeding period (1.34 ± 0.42 min) than males in the O- group (1.20 ± 0.39 min) and females with blood type O+ had a shorter bleeding time (1.30 ± 0.40 min) than females in the O- group (1.39 ± 0.37 min). At p< 0.05, all these variations found were statistically important. In conclusion, the current research shows that individuals in the blood group O+ typically have shorter bleeding periods than O-. In O+ males, bleeding time is prolonged compared to O+ females and prolonged in O- females compared to O- males. O+ males seem to have longer bleeding time within the gender than O- males, while O+ females have shorter bleeding time than O- females. In conclusion, in blood group O individuals, the presence of antigen D (rhesus factor) tends to be associated with decreased bleeding time relative to blood group O individuals without rhesus factor. However, the latest investigation has not demonstrated the same pattern in males. To elucidate these findings, we propose further studies: an elaborate general and gender-based analysis on potential genetic interactions between VwF and antigen D.

Author(s) Details

M. A. Egbejimi
Department of Human Physiology, Niger Delta University, Bayelsa State, Nigeria.

P. P. K. Joffa
Department of Human Physiology, Niger Delta University, Bayelsa State, Nigeria.

W. Koikoibo
Department of Human Physiology, Niger Delta University, Bayelsa State, Nigeria.

P. P. Erigbali
Department of Human Physiology, Niger Delta University, Bayelsa State, Nigeria.

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