The Problem of Chronic Oxidative Stress and the Systemic Indirect Ozone Therapy as a Possible Solution

A significant number of studies have found that unhealthy habits, such as a high-fat, high-salt diet, poor physical activity, and cigarette smoke, are a direct or indirect cause of cardiovascular disease, chronic respiratory disease, diabetes, and neurodegenerative diseases. A major increase in circulating reactive oxygen species (ROS), proinflammatory cytokines, and acute-phase proteins is the primary cause of death in all of these diseases. As a result, in addition to promoting healthy diets and minimising alcohol and tobacco use, it appears that correcting chronic oxidative stress during the development of chronic pathology is important. As a consequence, anti-hypertensive, anti-cholesterolemic, and anti-diabetic medications must be paired with a modulator capable of re-establishing the oxidant/antioxidant balance in cells. The medical community tends to disregard the promising biochemical and clinical effects of judicious application of ozone in the atrophic form of ARMD, chronic vasculopathies, Type II diabetes, chronic obstructive pulmonary disease (COPD), wound healing disorders, orthopaedics, and dentistry. The fact that ozone therapy can be used to treat a variety of diseases has been ridiculed by sceptical scientists who are unaware that when ozone is dissolved in plasma water, it reacts immediately with antioxidants and polyunsaturated fatty acids, generating two messengers capable of activating blood, endothelial, and a variety of parenchyma cells, all of which have different functions and are responsible for different diseases. The use of systemic indirect ozone therapy to treat chronic oxidative stress and associated pathologies is a safe and successful process.

Author (s) Details

Dr. Emma Borrelli
Postgraduate Course of Oxygen Ozone Therapy, Department of Medical Biotechnologies, University of Siena, Italy.

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