Preliminary Report on Scintimetric Evaluation of the Rheumatoid Arthritis Involvement by Dr. V. Siva’s Retention Ratio

The aim of this study is to demonstrate the value of Scintimetric Characterization of tracer activity uptake in Rheumatoid arthritis-affected joints in bone scans.

Materials and Methods: Bone scans for bone and joint pains revealed the existence of skeletal hot spots in three out of five patients with reported Rheumatoid arthritis. By repeating the 24 hr delayed bone scans, they were subjected to the scintimetric assessment of the skeletal hot spots by Dr. V. Siva’s retention ratio. In 3 hour and 24 hr bone scans, maximum counts were calculated for 58 skeletal hotspots seen in different joint spaces. They were tabulated, and Dr. V. Siva’s Retention Ratio for the last 24 hours was measured and analysed.

The mean was 5.91 0.35, and the standard error of the means was 0.3496. The estimated standard deviation was 2.9734 and the estimated variance was 8.8408. By HOJO’s adjustment, the average variance was 6.6306 and the estimated standard deviation was 2.575 for this sample size. Owing to the limited size of the Sample population, this was inevitable.

Conclusion: The scintimetric assessment of skeletal hotspots in Rheumatoid Arthritis patients revealed a definitive benign benefit, according to this report. This could serve as a solid baseline from which to evaluate patient response and progression.

Author (s) Details

V. Sivasubramaniyan
Department of Nuclear Medicine & Molecular Imaging, Sri Aurobindo Institute of Medical Sciences, Sri Aurobindo University, Indore, Madhyapradesh, India and Department of Physics, Sri Sathya Sai Institute of Higher Learning, Vidyagiri, Prasanthinilayam, Andhra Pradesh, India.

K. Venkataramaniah
Department of Physics, Sri Sathya Sai Institute of Higher Learning, Vidyagiri, Prasanthinilayam, Andhra Pradesh, India.

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