Retrospective Analysis of Scintimetric Characterization of Primary Tumors by Dual Phase PETCT Study

The aim of this retrospective study of the scintimetric characterization of primary tumours of different cancers using dual step PETCT scans is to prove the utility of Rong’s Retention ratio and Dr. V. Siva’s modification of RRI.

The SUV max values were obtained in the Early and Delayed PETCT scans using the ROI method over the FDG avid primary sites in the proven cases of different cancers. The PETCT scans were performed using the GE Discovery IQ unit one and four hours after receiving an I.V injection of 5 to 10 mCi of F18-FDG following an overnight quick. GE’s Advantage 4.7 software was used to perform the image analysis and measure the SUV. The determined SUV max was used to arrive at the Rongs Retention Index (RRI) and Dr. V. Siva’s adjustment of RRI, which included a total of 19 primary sites in different locations. The data was tallied and analysed.

The retention ratio of Rong had a very narrow range with a lot of overlap. Dr. V. Siva’s RRI modification, on the other hand, showed much broader values with a clear cutoff stage. The statistical analysis of the data shows that Dr. V. Siva’s RRI adjustment has a strong correlation with Rong’s Retention Index (RRI).

Conclusion: It can be inferred that scintimetric characterization of primary tumours of different cancers is possible and can be helpful in identifying primary malignancies.

Author (s) Details

V. Sivasubramaniyan
Department of Nuclear Medicine & Molecular Imaging, Sri Aurobindo Institute of Medical Sciences, Sri Aurobindo University, Indore, Madhyapradesh, India and Department of Physics, Sri Sathya Sai Institute of Higher Learning, Vidyagiri, Prasanthinilayam, Andhra Pradesh, India.

Sai Shiv Narayan
SSSIHL, India.

K. Venkataramaniah
Department of Physics, Sri Sathya Sai Institute of Higher Learning, Vidyagiri, Prasanthinilayam, Andhra Pradesh, India.

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