On the Molecular Filters in Cochlea Transduction: A Scientific Explanation

The focus of this article is on the cochlear transduction for low-level sound intensities, which correspond to areas near the threshold of perception. The modern definition of molecular filters extends the basic cochlea mechanics, allowing discussion of the transduction process at the molecular level in the spacetime domain. The stereocilia of each inner hair cell are expected to be used to construct the molecular filters. The molecular filters are thought to be the sensors in the feedback loop. The zero compensation approach is used to test the moving wave form on the basilar membrane, which involves outer hair cells as well as the tectorial membrane. Aside from compensation, the feedback loop, which is spatially distributed throughout the cochlea, takes control of the tectorial membrane strain field produced by the outer hair cells and uses it as the mechanism for sound transduction’s automatic gain control. The low values of basilar membrane deformations are also verified by computational simulations of moving waves for actual sound intensities.

Author (s) Details

Valeri Goussev
Research Center, Jewish Rehabilitation Hospital, Laval, Canada.

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