A Detailed Morphology and Histological Study of Placenta in Normal and Diabetic Pregnancies

Introduction: Many physiological alterations that enhance insulin resistance are generated by pregnancy in a diabetogenic situation. The placenta is a vital organ for the developing foetus, as well as the human body’s most accessible organ. Glucose tolerance has decreased by the third trimester of a typical pregnancy, although insulin levels in the blood have grown.

Aim: To determine the pregnancy’s outcome, the placenta of a normal pregnancy is compared to the placenta of a diabetic pregnancy.

The current investigation used 50 placenta specimens with intact umbilical cords acquired from the Department of Obstetrics and Gynecology as part of a case-control study.

The shape and weight of the placenta varied slightly. The control group’s mean placenta weight was 452.80 grammes, with a standard deviation of 140.93 grammes, while the case group’s mean placenta weight was 406.00 grammes, with a standard deviation of 210.31 grammes. The mother’s random blood sugar was substantially higher in the control group than in the cases (t=2.91, p0.01).

According to the current study, there was a tendency for placental weight and new-born weight to increase in complex pregnancies when compared to normal pregnancies. This showed an earlier diagnosis and adherence to the treatment strategy in diabetes pregnancies.

Author (S) Details

Durgesh Singh
Department of Anatomy, Shaikh-ul-Hind Maulana Mahmood Hasan (Government) Medical College, Saharanpur, Uttar Pradesh, India.

Shashi Prabha Singh
Department of Biochemistry, Shaikh-ul-Hind Maulana Mahmood Hasan (Government) Medical College, Saharanpur, Uttar Pradesh, India.

Priti Sinha
Department of Anatomy, Shaikh-ul-Hind Maulana Mahmood Hasan (Government) Medical College, Saharanpur, Uttar Pradesh, India.

Neha Gupta
Department of Anatomy, Shaikh-ul-Hind Maulana Mahmood Hasan (Government) Medical College, Saharanpur, Uttar Pradesh, India.

Rakesh Sharma
Department of Biochemistry, Shaikh-ul-Hind Maulana Mahmood Hasan (Government) Medical College, Saharanpur, Uttar Pradesh, India.

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