Study on Mammary Analogue Secretary Carcinoma: A Rare Salivary Gland Tumor

Introduction: Salivary gland tumours that are histologically comparable to breast secretory carcinomas are known as mammary analogue secretary carcinomas. Adults between the ages of 45 and 65 are the most affected. It is usually a slow-growing, low-grade cancer with a favourable prognosis.

The goal of this study was to look into the clinicopathological characteristics of mammary analogue secretary carcinoma of the salivary glands.

Case Report: We are reporting on the case of a 47-year-old woman who has had swelling behind her left ear for the past seven years. It grew gradually, painlessly, and steadily. A 4 x 3 cm enlargement was discovered immediately below the left ear lobule on inspection. It had a nontender, hard, uneven shape with a smooth surface, minor movement, and pinchable overlaying skin. Fine needle aspiration cytology revealed a benign tumour with cystic changes (FNAC). On a contrast enhanced computed tomography scan, a lobulated hypodense lesion measuring 24 x 35 x 32 mm with internal septations and wall enhancement was discovered at the predicted position of the superficial and deep lobes of the left parotid gland. After a left full conservative parotidectomy, histopathology revealed secretory analogue mammary cancer. She was then given radiation as a post-operative treatment. Patient is currently disease-free and is being followed up on on a regular basis.

Conclusion: Mammary analogue secretory carcinoma is frequently a low-grade tumour with a good prognosis. Immunohistochemistry confirms the presence of S-100 protein and mammaglobin.

Author (S) Details

Shashikant Anil Pol
Department of ENT, Government Medical College and Hospital, Chandigarh, India.

Surinder K. Singhal
Department of ENT, Government Medical College and Hospital, Chandigarh, India.

Nitin Gupta
Department of ENT, Government Medical College and Hospital, Chandigarh, India.

Himanshu Bayad
Department of ENT, Government Medical College and Hospital, Chandigarh, India.

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