Electrophysiological Studies in Newly Diagnosed Cases of Hypothyroidism

The goal of this study was to look at how electrophysiological changes in nerve conduction, brainstem auditory evoked potentials (BAEP), and visual evoked potentials (VEP) changed in hypothyroid patients.

Materials and Procedures: Sixty newly diagnosed hypothyroidism patients and an equal number of age-matched controls were enrolled in the study. The latencies, conduction velocities, and amplitude of motor nerves such the median, ulnar, common peroneal, and tibial nerves, as well as sensory nerves like the median and sural nerves, were measured in both hypothyroid patients and controls.All of the participants had their brainstem auditory evoked potentials (BAEPs) and visual evoked potentials (VEPs) recorded. The data was collated and statistically analysed to see if there were any electrophysiological differences between hypothyroid patients and healthy controls.

The median, ulnar, tibial, and sural nerves had a statistically significant increase in latency, as well as a drop in conduction velocities of all the examined nerves and a decline in amplitude of the median, tibial, and sural nerves in hypothyroid people. There was a statistically significant increase in latencies, interpeak latencies, and decreases in amplitudes of BAEP waves in hypothyroid people, as well as a statistically significant increase in VEP P100 delay.

Conclusion: Our findings suggest that peripheral and central neuropathy develops early in hypothyroidism patients, and that electrophysiological investigations of such people can help with early detection and treatment of neurological issues caused by thyroid hormone deficiency.

Author (S) Details

Naveenta Gupta
Department of Physiology, Guru Gobind Singh Medical College, Faridkot – 151203, Punjab, India.

Monika Arora
Department of Medicine, Guru Gobind Singh Medical College, Faridkot – 151203, Punjab, India.

Rajiv Sharma
Department of Physiology, Guru Gobind Singh Medical College, Faridkot – 151203, Punjab, India.

Khushdeep Singh Arora
Department of Physiology, Dasmesh Institute of Research and Dental Sciences, Faridkot – 151203, Punjab, India.

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