Studies on Proximate Composition, Phytochemical and Antimicrobial Screening of the Methanol and Acetone Extracts of Vitex doniana Fruit Pulp

The phytochemical components and antibacterial activity of methanolic and acetone extracts of Vitex doniana (Sweet) fruit were studied to identify its biological potentials. According to the study, the fruit contains alkaloids, flavonoids, saponins, phenols, tannins, steroids, and cardiac glycoside. Moisture 10.00 percent, ash 18.00 percent, crude fibre 4.50 percent, crude protein 0.60 percent, carbohydrate 43.20 percent, and crude lipids 23.70 percent were the proportion proximate composition of the plant’s fruit. Elemental analysis verified the existence of calcium, magnesium, potassium, and sodium. analysis. The methanolic and acetone extracts of the plant’s fruit were tested against Escherichia coli, Staphylococcus aureus, Pseudomonas areuginosa, and Klebsiella pnuemoniae using the agar (Mullen-Hinton) diffusion method. For all concentrations (1000, 500, and 250 mg/ml), the zone of inhibition for the methanol extract ranged from 10.50 to 21.00 (mm). At a dosage of 1000mg/ml, the acetone extract only reduced Escherichia coli growth until 7.50mm. According to the research, the fruit extracts contain antimicrobial qualities and could be utilised to treat a wide range of ailments and malnutrition.

Author (S) Details

Dr. A. E. Aiwonegbe
Department of Chemistry, University of Benin, Benin City, Nigeria.

J. U. Iyasele
Department of Chemistry, University of Benin, Benin City, Nigeria.

N. O. Izevbuwa
Department of Chemistry, University of Benin, Benin City, Nigeria.

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