Determining the Physiological Mechanisms Involved in Longer Life Span!

Ageing is without a doubt the most perplexing trait that occurs in humans. Highly specialised technologies are emerging for the entire treatment of ageing and associated disorders, revealing important insight into the underlying mechanisms and providing new hope for previously treatable diseases. Previous studies have discovered a correlation between human social interactions and life expectancy. There is a drop in mitochondrial activity as well as changes in nuclear chromatin as people get older. Multiple organ failure is linked to animal ageing, while in humans, age-related degeneration is the predominant factor. Naked mole-rats with low levels of circulating methionine lived longer, implying a natural life-extension phenotype comparable to that seen in methionine-restricted species. As a result of health-improvement measures, people have lived longer. Humans of varied families age at different rates, and those who have outlived their peers provide promise for understanding why some people age more slowly than others. The purpose of this research is to identify the most important factors that contribute to lifespan. The newest advances in cutting-edge technology applied across the realm of ageing research, including developing model organisms, high-throughput techniques, and machine-driven approaches, are described in this paper. Overall, this collection of articles will provide you a taste of what will be driving the field forward.

Author (s) Details

Kartheek R. Balapala
School of Medicine, Copper belt University, Zambia.

Victor Mwanakasale
School of Medicine, Copper belt University, Zambia.

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