Determination of Phytochemicals as Potential Inhibitors of Matrix Metalloproteinases (MMPs) with Special Reference to Breast Cancer

 

Breast cancer is the most frequent cancer in women in India and around the world. Metastasis and secondary tumour growth are the leading causes of mortality and poor clinical prognosis in most malignancies, including breast tumours, and metastasized cancers remain essentially untreatable even with modern therapeutic options. MMPs, a family of zinc-dependent endopeptidase enzymes, play an important role in the regulation of metastasis and tumour formation, making them potential therapeutic targets for preventing metastasis. Therapeutic using phytochemical substances has the potential to lessen treatment adverse effects while also lowering treatment costs. The goal of this study is to look at the potential of four different phytochemicals, resveratrol, theaflavin, curcumin, and all-trans retinoic acid, as MMP inhibitors, with a focus on breast cancer.

Author (S) Details

Anirban Roy
Post Graduate Department of Biotechnology, St. Xavier’s College (Autonomous), Kolkata, 30 Mother Teresa Sarani, Kolkata 700016, West Bengal, India.

Indira Chakraborty
Post Graduate Department of Biotechnology, St. Xavier’s College (Autonomous), Kolkata, 30 Mother Teresa Sarani, Kolkata 700016, West Bengal, India.

Aniruddha Banerji
Post Graduate Department of Biotechnology, St. Xavier’s College (Autonomous), Kolkata, 30 Mother Teresa Sarani, Kolkata 700016, West Bengal, India.

View Book :- https://stm.bookpi.org/IDHR-V5/article/view/3969

 

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