Study on Cissus quadrangularis Linn: An Insilico Approach towards the Anti-inflammation and Anticancer

The medicinal plant Cissus quadrangularis is native to Asia and Africa. It is utilised in traditional medical systems such as ayurveda, siddha, unani, and homoeopathy. This plant’s medicinal components are thought to be particularly useful for a variety of diseases. The phytochemical examination of the plant Cissus quadrangularis began with ethanobotanical and traditional usage of the plant. The study’s major goal is to use an insilico method to determine the potential of a few isolated phytochemicals from this plant against cancer and inflammation. The plant’s stem was extracted with Petroleum ether, Ethyl acetate, Chloroform, and Ethanol in a series of solvents. The crude extract was choromatographed in a column. Ascorbic acid, quercetin, phytol, and Luteolin were discovered among the 20 components extracted. After that, the phytochemicals were molecular docked in Auto dock 4.2 to see if they had any pharmacological activity. These molecules can be carried over for invivo investigation, according to the findings.

Author(S) Details

Vidya Edathil
Department of Chemistry, PSGR Krishnammal College for Women, Coimbatore, India.

Selvi Gopal
Department of Chemistry, PSGR Krishnammal College for Women, Coimbatore, India.

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