Thrombocytosis Associated with Lower Respiratory Tract Infection in Pediatric Population: A Two-year Retrospective Study

Thrombocytosis is an inflammatory sign associated with a variety of clinical disorders. Increased levels of thrombopoietin, interleukin-6, interleukin-1alpha, interleukin-8, and tumour necrosis factor alpha are linked to inflammatory thrombocytosis. The goal of this study was to determine the prevalence and relevance of thrombocytosis in children with a lower respiratory tract infection.

Materials and Methods: The current study was retrospective in nature, and it was conducted on 200 children aged up to 6 years who were hospitalised for a lower respiratory tract infection over the course of 24 months. Patients were divided into two groups: those who had thrombocytosis and those who did not.

The results showed that out of 200 youngsters, 110 (55%) had thrombocytosis and 90 (45%) did not. Ten percent of children with thrombocytosis had pneumonia, 40 percent had severe pneumonia, and 60 percent (54.5%) had extremely severe pneumonia. 50 (55.5%) of the 90 children without thrombocytosis had pneumonia, 10 (11%) had severe pneumonia, and 30 (33%) had very severe pneumonia.

Conclusions: Children with lower respiratory tract infections have long been linked to thrombocytosis, according to this study. The duration of hospitalisation and severity of pneumonia were both higher in the group with a high thrombocyte level.

Author(S) Details

Priyanka Kiyawat
Department of Pathology, MGM Medical College and M. Y. Hospital, Indore, India.

Ashok Panchonia
Department of Pathology, MGM Medical College and M. Y. Hospital, Indore, India.

Sonal Meshram
Department of Pathology, MGM Medical College and M. Y. Hospital, Indore, India.

Shailendra Singh Thakur
Department of Pathology, MGM Medical College and M. Y. Hospital, Indore, India.

View Book:- https://stm.bookpi.org/ETDHR-V1/article/view/5206

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