Screening of Donated Blood for Transfusion-transmitted Infections by Serology and Response Rate to Notification of Reactive Results in Tertiary Care Institution

Background: Blood safety Healthy donors are used to start the transfusion process. Notifying and counselling reactive donors is an important aspect of reducing transfusion-transmitted illnesses (TTIs). Historically, serologic testing for transfusion-transmitted illnesses has been the cornerstone of blood screening. The goal of this study was to look at trends in the prevalence of transfusion-transmissible infectious diseases among blood donors, as well as to notify them and measure their response rate. Donor counselling and notification preserve the donor’s health and prevent subsequent transmission of infectious illnesses.

Methods: By serology, 38707 blood donations were screened for TTIs, such as HIV, HBV, HCV, and syphilis, as well as Malarial Parasite. Anti-HIV antibody, anti-HCV antibody, and HBsAg ELISA testing, RPR test for syphilis, Rapid card test for Malaria All reactive donors were retested in duplicate and told of their results by telephone communication.

The number of cases with reactive screening test results was 341 (0.88%). (0.617 percent HBV, 0.016 percent HCV, 0.134 percent HIV, 0.08 percent syphilis, 0.031 percent Malaria). Only 179 contributors (52.5%) responded to the notice. When compared to replacement donors, the response from volunteer donors was better (54.1 percent versus 40.7 percent ). Only 101 (57.22%) donors responded after their first visit to the referral clinic.

Conclusion: Our research shows that TTIs are common among blood donors, emphasising the significance of thorough donor counselling and notification of TTI status to all reactive donors who choose to receive it.

Author(S) Details

Rohit Vasantbhai Bhalara
Department of Pathology, Pandit Dindayal Upadhyay Medical College, Rajkot, India.

Payal Shah
Department of Pathology, Pandit Dindayal Upadhyay Medical College, Rajkot, India.

Ravi Kirit Kumar Kothari
Department of Pathology, Pandit Dindayal Upadhyay Medical College, Rajkot, India.

Gauravi Dhruva
Department of Pathology, Pandit Dindayal Upadhyay Medical College, Rajkot, India.

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