A Cross-sectional Study Highlighting Awareness about FDA Announcement on Voluntary Recall of Ranitidine among Physicians and Pharmacists in and Around Chennai, India

Ranitidine is a histamine-2 (H2) blocker that lowers the amount of acid produced by the stomach. The medicine was recalled in September 2019 by the Food and Drug Administration (FDA), the European Medicines Agency (EMA), and Health Canada owing to impurities N-nitrosodimethylamine (NDMA). According to laboratory examinations, NDMA is a carcinogen.

The study’s goal is to determine how well physicians and pharmacists in and around Chennai are aware of the ranitidine recall announcement and related difficulties.

Materials and Methods: A questionnaire was administered to 198 physicians and 113 pharmacists who were enrolled in the study as part of a descriptive, cross-sectional investigation. The participants’ awareness, knowledge, and concerns about recall notification were collected.

Results revealed that only 75% of survey participants were aware of the notification and the difficulties it raised, with urban individuals outnumbering rural ones by a wide margin. When the notification was widely publicised, the grounds for the notification were unknown. The bulk of people who were unfamiliar with the ranitidine recall warning and related difficulties were from rural areas, according to the findings.

Conclusion: The level of awareness among physicians and pharmacists was found to be insufficient. Physicians and pharmacists are the most responsible healthcare practitioners, and they must be aware of any medication-related alerts issued by regulatory agencies.

Author(S) Details

Rukaiah Fatma Begam
Faculty of Pharmacy, SRM Institute of Science and Technology, Chennai 603203, India.

Swathi Suresh
Faculty of Pharmacy, SRM Institute of Science and Technology, Chennai 603203, India.

Yamuna Ravikumar
Faculty of Pharmacy, Vels Institute of Science Technology and Advanced Studies, Chennai, 600117, India.

Deepa Natarajan
Faculty of Pharmacy, Saveetha Institute of Medical and Technical Sciences, Chennai, 602117, India.

Ramaiyan Velmurugan
Faculty of Pharmacy, Saveetha Institute of Medical and Technical Sciences, Chennai, 602117, India.

View Book:- https://stm.bookpi.org/CAPRD-V8/article/view/5652

Leave a Reply

Your email address will not be published.

Previous post Determination of Solid Dispersion by Fluidized Bed Processing: A Platform for Enhancement of Solubility and Dissolution
Next post A Stability Indicating RP-HPLC Method Validation for Simultaneous Estimation of Linagliptin and Empagliflozin in Pharmaceutical Dosage Form