Development of Oral Herbal Male Contraceptive

Background: More study on male contraception is encouraged since population management is seen as a key step toward global health. Despite the fact that there are many synthetic contraceptives available, they all have different negative effects. When compared to condoms, several male contraceptive treatments, such as hormonal, pharmacological, and immunological therapies, were researched over a long period of time and found to have good antifertility efficacy with low failure rates.

The idea of herbal contraceptives, which are an effective technique to limit animal and human reproduction, is the emphasis of this chapter. The focus of this review was on herbal medicinal plants and plant extracts that have been found to have antifertility effects in men. Plants having reported animal research and some with human studies for antifertility effects, as well as their dosages, chemical contents, and mechanism of action for the antifertility impact of the plants, are all considered in the review. This chapter also covers the stages of sperm formation, hormone production, and the mechanism of male contraceptives.

Conclusion: In terms of the current review’s applicability, it might be extremely useful in the development of plant monographs and recommendations for their use. Many of the plants listed here could be used as alternative oral fertility regulators in males. As a result, greater research into the chemical and biological characteristics of these less-explored plants is needed to evaluate their contraceptive efficacy as well as any negative effects, so that these compounds can be utilised reliably to manage male fertility. New inventions are needed in this field to focus on more current, more potent pharmaceuticals with less toxic components that are self-administerable, less expensive, and entirely reversible.

Author(S) Details

Akash Yadav
IEC University, Baddi, Himachal Pradesh-174103, India.

Shivangi Sharma
Saraswati College of Pharmacy, Gharuan, Mohali, Punjab-140413, India.

Shahid Nazir Wani
IEC University, Baddi, Himachal Pradesh-174103, India.

Kirti Kaushal
IEC University, Baddi, Himachal Pradesh-174103, India.

Priya Sharma
IEC University, Baddi, Himachal Pradesh-174103, India.

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