More Reliable Approach than Blood Glucose Value is Needed in Assessment of Cell Metabolism

We looked examined how diverse medical situations affected blood glucose levels and metabolic states. Clinical recommendations indicate the primary therapy objective for diabetes mellitus to be near-normoglycaemia. According to this hypothesis, euglycemia and eumetabolism go hand in hand, while hyperglycemia is a sign of dysmetabolism. The blood glucose levels may only be regarded as a broad metabolic indicator with clear limits, the scientists conclude. The primary ideas of this claim are that acute hyperglycemia does not always result in dysmetabolism and that euglycemia is not always accompanied with eumetabolism. When blood glucose levels are the same, several biochemical energy-producing systems can sustain the same cell metabolic function. Both a positive and negative metabolic balance of cell metabolism may take place at the same blood glucose level. Blood glucose levels that are normal or increased might be used to identify the acute stress state. This indicates that there is no necessary connection between the actual blood glucose value and the metabolic state, i.e., the increased metabolic activity is not represented by the concomitant often normal blood glucose tests. As a result, establishing near normoglycemia continues to be the major therapeutic objective in the treatment of diabetes. Another discovery is that persistent hyperglycemia serves as both a marker and a cause of dysmetabolism. The use of insulin may benefit dysmetabolic conditions that have a variety of causes. The importance of chronic stress is highlighted in regard to how different dysmetabolic states develop and interact with one another. The difference between blood glucose levels and cellular metabolism is supported by the transporter nature of blood glucose values, this value reflects

Author(s) Details:

Kornel Simon,
Department of Internal Medicine, County Hospital, Siofok, Hungary.

Istvan Wittmann,
Department of Medicine and Nephrological Center, Faculty of Medicine, University of Pecs, Pecs, Hungary.

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Keywords: Blood glucose, euglycaemia, eumetabolism, dysmetabolism, diabetes, chronic stress

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