Effect of Ethanolic Extract of Solanum torvum Leaf on Liver of Treated Rats: A recent study approach

 In conventional medicine, the plant solanum torvum is frequently employed. This study’s objective was to assess how treated Wistar rats’ livers responded to an ethanol extract of Solanum torvum leaf. S. torvum leaves that had just been collected were shade-dried and milled into a fine powder. ethanol was macerated with 500 g of powdered plant material for 72 hours. Wistar adult male rats weighing between 150 and 200 g were administered the extract. Following the slaughter of the animals, blood and tissue samples were collected, extracted, and analysed in accordance with procedure. The results of this investigation show that administration of an aqueous extract of S. torvum increased levels of total and conjugated bilirubin as well as liver enzyme activity in a dose-dependent manner. However, there was no change in the levels of conjugated and total bilirubin or the enzyme activity between the 100 mg/kg of S. torvum extract and the control (P>0.05). Conclusion: Solanum torvum, which is typically thought to be safe for human ingestion, may actually be hepatotoxic at large quantities.

Author(s) Details:

Nweke Elizabeth Obioma,
Department of Human Anatomy, Chukwuemeka Odumekwu Ojukwu University, Uli, Nigeria.

Nwizu Olive Ogechi,
Department of Human Anatomy, Chukwuemeka Odumekwu Ojukwu University, Uli, Nigeria.

Please see the link here: https://stm.bookpi.org/CAPR-V5/article/view/7772

Keywords: Bilirubin, enzyme, liver, solanum torvum

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