Antibiotics Susceptibility and Resistance Pattern of Bacteria Pathogens of UTIs among Pregnant Women in Nigeria

This study set out to document the antibiotic sensitivity and resistance patterns of the bacteria pathogens that cause UTIs in pregnant women in Bida, North Central, Nigeria, as well as to assess the degree to which these bacteria pathogens are drug-resistant in the general population. The study was conducted retrospectively between August 2012 and December 2013. 516 bacterial pathogens that were discovered at the Federal Medical Centre’s Medical Microbiology Department in Bida, Niger State, North Central, Nigeria, were used in this inquiry. Escherichia coli 342 (66.3%) was the most prevalent of these 516 bacterium isolates, followed by Staphylococcus aureus 162 (31.4%), Klebsiella specie 6 (1.2%), Serratia marcescens 4 (0.8%), and Proteus specie 2 (0.4%), which had the lowest prevalence. Nitrofurantoin (58.5%) and Nalidixic acid (34.5%) had the greatest overall susceptibility patterns for uropathogens, and both of these patterns were statistically significant (Nitrofurantoin p=0.000, Mean value 75.5, and Nalidixic acid p=0.000, Mean value 44.5). The most common strain of Escherichia coli is susceptible to Nitrofurantoin at a rate of 61.4% and Nalidixic Acid at a rate of 42.1%, respectively. A routine microbiological investigation and susceptibility test should be performed before to administering any drugs to a patient. The government ought to implement regulations that forbid the purchase and usage of antibiotics without a prescription from licenced medical professionals.

Author(s) Details:

Akobi Oliver Adeyemi,
Department of Medical Microbiology, Federal Medical Centre, Bida, Niger-State, Nigeria.

Emumwen Evbaziegbere Gideon,
Department of Medical Microbiology, Federal Medical Centre, Bida, Niger-State, Nigeria.

Uzoigwe Eunice Ogochukwu,
Department of Medical Microbiology, Federal Medical Centre, Bida, Niger-State, Nigeria.

Uyigue Paulinus Osarodion,
Department of Medical Laboratory Science, Achiever University, Owo, Ondo State, Nigeria.

Akobi Evelyn Chimerenma,
Department of Nursing, Federal Medical Centre, Bida, Niger State, Nigeria.

Akinola Sikiru Ajibola,
Oyo State Hospital Management Board, Secretariat, Ibadan, Nigeria.

Emumwen Ehiosu Favour,
Medical Laboratory Services, Fed. Polytechnic Medical Centre, Bida, Niger-State, Nigeria.

Please see the link here: https://stm.bookpi.org/CODHR-V3/article/view/7903

Keywords: Antibiotics susceptibility, uropathogen, urinary tract infections