Antibacterial and Antifungal Activity of Carica papaya L. Seed Extracts: A Recent Study

Antimicrobial powers are plentiful in medicinal plants. Many strong and beneficial drugs are derived from curative plants, that are secondhand in various nations. Carica fruit roots, crops, bark, children, and pulp have existed shown to have healing belongings. It has happened used to treat conditions in the way that rash, warts, sinusitis, cutaneous tubercles, belief in bad outcome, blood pressure, amenorrhoea, and muscle spasm. Carica fruit is a more influential medicinal spice namely used as a traditional medicine for the situation of various disorders all over the experience. Carica fruit sources were approved and rooted in few studies for their persuasive anthelmintic properties against nematodes in the direction of mammals. It is a appendage of the Caricaceae family. Carica fruit (Papaya) sources were gleaned using a soxhlet machine utilizing solvents to a degree intoxicating, flammable liquid, and chloroform. The completely clean and antifungal venture of extracts at miscellaneous concentrations (50, 100, and 150 μg/ml) was examined utilizing the agar plate spread method accompanying three gramme helpful, three gramme negative microorganisms, and two fungal species. For decontaminating and antifungal projects, gentamicin and fluconazole were chosen as standard cures. Methanol and anesthetic extracts shy gramme negative germs in a more excellent manner than intoxicating extract. Ethanol and kill extracts demonstrated a best district of hindrance (10-15 mm) than methanol extract for gramme definite microorganisms. Candida albicans shown a 15, 16 mm district of inhibition in toxin and flammable liquid extracts at concentrations of 150 μg/ml, individually. Similarly, Aspergillus niger exhibited a district of restriction of 11, 13 mm in 150 μg/ml methanol and kill extracts, individually. According to the verdicts of these investigations, Carica fruit beginning extracts have very forceful antibacterial and antifungal venture in two together flammable liquid and chloroform extracts.

Author(s) Details:

S. Sundar,
Department of Pharmacology, Vijaya Institute of Pharmaceutical Sciences for Women, Enikepadu, Vijayawada, Krishna District, Andhra Pradesh, India.

K. Padmalatha,
Department of Pharmacology, Vijaya Institute of Pharmaceutical Sciences for Women, Enikepadu, Vijayawada, Krishna District, Andhra Pradesh, India.

A. Jayarami Reddy,
Department of Pharmacology, Vijaya Institute of Pharmaceutical Sciences for Women, Enikepadu, Vijayawada, Krishna District, Andhra Pradesh, India.

A. Bhavana,
Department of Pharmacology, Vijaya Institute of Pharmaceutical Sciences for Women, Enikepadu, Vijayawada, Krishna District, Andhra Pradesh, India.

N. K. S. Neeraja,
Department of Pharmacology, Vijaya Institute of Pharmaceutical Sciences for Women, Enikepadu, Vijayawada, Krishna District, Andhra Pradesh, India.

S. Jaya Sai Keertana,
Department of Pharmacology, Vijaya Institute of Pharmaceutical Sciences for Women, Enikepadu, Vijayawada, Krishna District, Andhra Pradesh, India.

Please see the link here: https://stm.bookpi.org/CAPR-V10/article/view/8803

Keywords: Carica papaya seed extracts, antibacterial, antifungal, Zone of inhibition

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