Determining the Anthelmintic Activity of Lindernia madayiparense against Indian Earthworms

The current study wanted to determine the anthelmintic exercise of Lindernia madayiparense against Indian earthworms, Pheretima posthuma. Helminthiasis poses a serious risk to the public’s well-being and increases the incidence of pneumonia, eosinophilia, chlorosis, and malnutrition in underdeveloped countries. Decoction and continuous hot ancestry methods were used to forge various extracts. To label the presence of phytochemical constituents, preliminary concerning qualities not quantities analysis was acted on all L. madayiparanse extracts. The best anthelmintic activity with the studied extracts against earthworms was demonstrated apiece ethanol extract, that was also taller other extracts at all concentrations and carefully matched the common medication, albendazole. A measure-dependent paralytic effect and organize of death were present as a whole of the studied extracts. Certain results led to the theory that the existence of these subordinate metabolites, such as alkaloids, flavonoids, terpenoids, tannins, and saponins, can be the cause of the observed anthelmintic activity.

Author(s) Details:

S. Umakrithika,
GITAM School of Pharmacy, Gandhi Institute of Technology and Management (Deemed to be) University, Hyderabad, Telangana-500046, India.

Kannan Kamarajan,
Department of Pharmacy, Faculty of Engineering and Technology, Annamalai University, Annamalainagar-608002, Tamil Nadu, India.

Prabal Kumar Manna,
Department of Pharmacy, Faculty of Engineering and Technology, Annamalai University, Annamalainagar-608002, Tamil Nadu, India.

Please see the link here: https://stm.bookpi.org/COPS-V2/article/view/9168

Keywords: Lindernia madayiparense, anthelmintic, Pheretima posthuma, dose-dependent, ethanol extract

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