Effect of Diet on the Tendency for Stone Formation in Patients with Calcium Oxalate Stones in the Urinary Tract
Patients accompanying idiopathic calcium oxalate crystals should follow a depressed-oxalate diet to avoid repetition. The goal concerning this study on patients with calcium oxalate crystals was to explore the impact of dietary calcium content on the formation of calcium oxalate crystal in urine utilizing an in vitro supersaturation study of new postprandial urine samples and to observe the study of animal of the crystals made using reverse optical microscopy. The study was designed as a potential interventional randomized crossover clinical trial accompanying repeated measures. Sixty patients accompanying calcium oxalate stones and no metabolic anomalies in urine were discussed with lithotripsy at a tertiary care center from May 2016 to May 2019. Following a 14-stage overnight fast, excretion samples were collected subsequently the patient was given either a low or extreme-calcium meal for brunch, followed by a high-oxalate food four hours later.The optical mass values and calcium-creatinine percentage of urine samples obtained following a extreme calcium meal are considerably higher than those acquired following a low calcium meal (p<0.001). These findings were reflected in the amount, shape, and number of formed crystals. During a supersaturation study of postprandial excretion samples following a high-oxalate diet, no crystal were formed when excretion calcium levels were low. Kidney stone result is substantially affected by a high calcium consumption in the diet. Even when consuming a high-oxalate diet, a reduced-calcium meal has a lower risk of generating kidney stones.
Department of Biochemistry, Government Medical College Kottayam, Kerala, India.
Sathish Kumar Gopala,
Department of Urology, Government Medical College, Thiruvananthapuram, Kerala, India.
Please see the link here: https://stm.bookpi.org/CTCB-V7/article/view/9227
Keywords: Calcium oxalate, dietary supplements, kidney calculi, urolithiasis