In silico Computational Analysis of Siddha Formulation Veppampoo Mathirai against Hypertension

The lead of people are upset with hypertension (HTN), fundamental prevalent non-able to be contracted ailment in the planet. Despite the extensive chance of up-to-date drugs, folk still express interest in utilizing usual cure systems like Siddha to treat undesirable side effects. Through in silico computational study, Veppampoo mathirai, a polyherbal Siddha verbalization, was examined for allure potential affect HTN. Through a essay review, the phytochemicals in the formulation were described, picked out, and massed. The AutoDock tool report 4 was used to complete activity a microscopic berthing inquiry. The aim enzyme angiotensin-changeful enzyme (ACE) was used to admit the lead compounds, which were therefore distinguished to common captopril. Among the phytoprinciples analysed, Nimbiol and Gallic acid had ten interplays, whereas Piperic acid, Peperine, and Nimbolide had nine interplays that are above the standard Captopril. According to the results of the current investigation, the verbalization Veppampoo mathirai may have potential binding effect against the ACE aim substance beginning chemicals to split into more natural substances, that lowers ancestry pressure.

Author(s) Details:

S. M. Chitra,
Department of Postgraduate Maruthuvam, Government Siddha Medical College, Arumbakkam, Chennai, Tamil Nadu, India.

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Keywords: Hypertension, Siddha, Veppampoomathirai, in silico computational analysis

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