A Review on the Pharmacological Effects of Curcumin in Diabetes, Cancer, and Neurodegenerative Diseases

As a diet-derivative agent, curcumin has been secondhand traditionally in many forms for the treatment of redness and pain but most of the recent studies exposed the role of curcumin as an antidiabetic, anti-malignant, anti-infectious, antidepressant, and antipsychotic power. This dietary supplement has the ability to block any of cells indicating pathways at various levels which underlies allure diverse effect. By modulating cell phases and interacting directly accompanying molecular targets like glutathione peroxidase, basic factor kappa-B containers, cyclooxygenase-2, hepatic superoxide dismutase, reactive oxygen species lump necrosis factors, etc. curcumin can avoid the development of cancer. In this division, we demonstrated the therapeutic belongings of curcumin in various cancers, neurodegenerative disorders, microbial contaminations, and diabetes interconnected with allure molecular pathways during preclinical troubles.

Author(s) Details:

Nidhi Agrawal,
Siddhi Vinayaka Institute of Technology and Sciences, Mangla, Bilaspur (C.G.)–495001, India.

Hasnain Raza,
Siddhi Vinayaka Institute of Technology and Sciences, Mangla, Bilaspur (C.G.)–495001, India.

Meenakshi Jaiswal,
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur (C.G.)-495009, India.

S. K. Lanjhiyana,
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur (C.G.)-495009, India.

Manoj Kumar Sahoo,
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur (C.G.)-495009, India.

Please see the link here: https://stm.bookpi.org/NAPR-V2/article/view/10599

Keywords: Curcumin, anti-diabetic activity, anti-oxidant activity, neurodegenerative diseases, anti-cancer activity