Schiff bases are versatile ligands that are generated by combining primary amines with carbonyl groups. Because of their broad range of biological activities, these compounds are extremely significant in the medical and…
Category: Chemistry and Biochemistry
Analysing the Impact of Nutritional and Environmental Epigenetics on Human Health and Disease
Environmental epigenetics is the study of how environmental factors influence cellular epigenetics and, as a result, human health. To control gene expression, epigenetic marks change the spatial conformation of chromatin. Behaviours, diet,…
Study on Proteomic Profiling of High-grade Glioblastoma: Aspects of Biomarkers
Author(s) Details Stanislav N. Naryzhny, Institute of Biomedical Chemistry, Pogodinskaya 10, Moscow, 119121, Russia and B. P. Konstantinov Petersburg Nuclear Physics Institute, National Research Center “Kurchatov Institute”, Leningrad Region, Gatchina, 188300, Russia….
Distribution of Proteoforms Numbers in a Human Cell according to Their Abundance is Following Zipf’s Law
The complex functional mechanisms of the cellular proteome are provided by the collaboration of thousands of protein components, protein species/proteoforms. Although recent methods do not yet enable us to obtain a complete…
Recent Study on Copper-Promoted One-Pot Approach: Synthesis of Benzimidazoles
For the production of various 2-arylaminobenzimidazoles, a simple, one-pot method was produced. For the first time, a copper catalyst promoted domino C–N cross-coupling reaction for the generation of 2-arylaminobenzimidazoles is used in…
Potential Anti-diabetic Activities from Edible Bird Nest and Its Hydrolysates
Edible bird’s nest (EBN) is traditionally regarded as a delicacy, with numerous health benefits believed to be sought after in Asia, especially China. The anti-diabetic properties of the EBN and its hydrolysate…
Discussion on the Possible Role of Molecular Vibration in Intracellular Signalling
The knowledge exchange inside the cell is extremely complicated. Physical signalling is expected to fulfil spatial and temporal aspects in addition to the well-studied chemical signalling. For several intracellular transport functions, the…
An In-vitro and In-vivo Study of Antioxidant Potential of Green Synthesized Flavonoid Loaded Mono and Bimetallic Nanoparticles
Nanotechnology’s remarkable performance has unwrapped the vision for creating mono and multimetallic nanoparticles with a wide variety of applications due to their distinct conduct. Gold and silver nanoparticles have made considerable strides…
Microwave Assisted Reactions for Synthesis of Bioactive Azaheterocycles
Azaheterocycles have gotten a lot of attention in recent years because of their common occurrence in many natural and synthetic products, as well as their wide range of biological activities. Simultaneously, greener…
Recent Approach on Determination of Impurities and Degradation Products/Causes for m-Iodobenzylguanidine Using HPLC-Tandem Mass Spectrometry
m-Iodobenzylguanidine hemisulfate (MIBGHS) is a precursor for radioiodine-labeled m-iodobenzylguanidine (MIBG), which is used as a radio-imaging and therapy agent for neuroendocrine tumours and myocardial sympathetic nerve activity. The purity of the precursor,…