Newsletter on Transfusion Research: September-2018

Transfusions of ‘old’ blood may harm some patients

Blood transfusions with the oldest blood accessible may well be harmful to a few patients, finds a team of researchers. The investigators suggest reducing the most blood storage limit from six to 5 weeks. [1]

Recommendations on RBC Transfusion in Critically Ill Children With Nonlife-Threatening Bleeding or Hemorrhagic Shock From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative.

To gift the recommendations and supporting literature for blood cell transfusions in critically unwell kids with harm developed by the medical specialty vital Care Transfusion and Anemia experience Initiative. Consensus conference series of international, multidisciplinary specialists in blood cell transfusion management of critically unwell kids. The panel of thirty-eight specialists developed evidence-based and, once proof was lacking, expert-based clinical recommendations yet as analysis priorities for blood cell transfusions in critically unwell kids. The harm subgroup enclosed 5 specialists. Electronic searches were conducted victimization PubMed, EMBASE, and Cochrane Library databases from 1980 to might 2017. The agreement was obtained victimization the analysis and Development/UCLA Appropriateness technique. [2]

The Pediatric Critical Care Transfusion and Anemia Expertise Initiative Consensus Conference Methodology.

This article describes the methodology used for medical specialty crucial Care Transfusion and Anemia experience Initiative accord Conference. A consensus conference of international consultants in medical specialty crucial care and transfusion medication, following standards set by the Institute of medication, victimization the analysis and Development/UCLA Appropriateness technique, sculptured once the medical specialty Acute respiratory organ Injury accord Conference. Topics concerning red blood cell transfusion in kids with or in danger for crucial unwellness were divided into 9 subgroups with a scientific review of the literature. The panel of thirty-eight content and 4 methodology consultants met 3 times over the course of two years and collaborated to develop evidence-based and, once proof was lacking, expert-based clinical recommendations in addition as analysis priorities for red blood cell transfusions in crucially unwell kids or those in danger for critical unwellness. [3]

Implementation of the Recommendations for RBC Transfusions for Critically Ill Children From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative.

To provide context for the implementation of the medical specialty essential Care Transfusion and Anemia experience Initiative recommendations for blood corpuscle transfusions together with a review of previous analysis concerning the implementation of transfusion pointers, efforts to facilitate implementation through Transfusion and Anemia experience Initiative, and to supply a framework for recommendation implementation. Review of existing clinical literature and outline of a comprehensive approach to implementation supported Implementation Science principles. The Transfusion and Anemia experience Initiative recommendations on blood corpuscle transfusions area unit supported clinical proof and aim to limit extra and probably harmful transfusions. previous efforts to use transfusion pointers embody the use of supplier education, native pointers, visual aids, prospective and retrospective audit and feedback similarly as processed call support tools; but, no single approach has been known as optimum for implementation in medical specialty essential care settings. [4]

Prevalence of Transfusion Transmissible Infections among Blood Donors in a Tertiary Care Hospital of Mysuru District – A Six Years Study

Introduction: intromission remains a considerable supply of transmissible infection in the Asian nation. The prevalence of transfusion-transmissible infections (TTIs) like Human immunological disorder Virus (HIV), viral hepatitis Virus (HBV), hepatitis C Virus (HCV), venereal disease and protozoal infection in blood donation is vital for evaluating blood safety and potential risks to the population.

Aims: to see the prevalence of HIV, HBV, HCV, venereal disease and protozoal infection among blood donors during a tertiary care hospital.

Study Design: A retrospective review of donor record over an amount of half-dozen years between 2009 to 2014 was done at the regional intromission center (RBTC) during a tertiary care hospital of Mysuru, Karnataka, India. [5]

Reference

[1] Transfusions of ‘old’ blood may harm some patients

Date: January 9, 2017, Source: Columbia University Medical Center (web link)

[2] Recommendations on RBC Transfusion in Critically Ill Children With Nonlife-Threatening Bleeding or Hemorrhagic Shock From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative.

Karam, O., Russell, R.T., Stricker, P., Vogel, A.M., Bateman, S.T., Valentine, S.L. and Spinella, P.C., 2018. Recommendations on RBC Transfusion in Critically Ill Children With Nonlife-Threatening Bleeding or Hemorrhagic Shock From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative. Pediatric critical care medicine: a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 19(9S Suppl 1), pp.S127-S132. (web link)

[3] The Pediatric Critical Care Transfusion and Anemia Expertise Initiative Consensus Conference Methodology.

Bembea MM, Valentine SL, Bateman ST, Wilson LM, Anton B, Harger N, Robinson KA. The Pediatric Critical Care Transfusion and Anemia Expertise Initiative Consensus Conference Methodology. Pediatric critical care medicine: a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 2018 Sep;19(9S Suppl 1): S93-7. (web link)

[4] Implementation of the Recommendations for RBC Transfusions for Critically Ill Children From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative.

Steffen, K.M., Bateman, S.T., Valentine, S.L., Small, S., Spinella, P.C. and Doctor, A., 2018. Implementation of the Recommendations for RBC Transfusions for Critically Ill Children From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative. Pediatric critical care medicine: a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 19(9S Suppl 1), pp.S170-S176. (web link)

[5] Prevalence of Transfusion Transmissible Infections among Blood Donors in a Tertiary Care Hospital of Mysuru District – A Six Years Study

Pallavi Prakash1*, Shreedevi S. Bobati1, and Vijaya Basavaraj1

1Department of Transfusion Medicine, JSS Medical College, and Hospital, JSS University, Mysuru, India  (web link)

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