Press Release on Eosinophilia Research: September-2018

Adults with eosinophilic esophagitis should consider a diet change

Dietary elimination could be a self-made methodology of treatment for adults with leukocyte redness, in keeping with a brand new study. leukocyte redness could be a chronic system malady caused by a buildup of white blood cells within the lining of the gullet. This buildup, that could be a reaction to food, allergens or acid reflux, will inflame or injure passage tissue, creating swallowing and uptake a challenge for patients. [1]

Lung Diseases Caused by Aspergillus and Pulmonary Eosinophilia

Aspergillus fumigatus is that the most frequent reason for flora respiratory organ malady in humans. The spectrum of Aspergillus airways malady ranges from allergic respiratory illness characterized by AN IgE-mediated immunologic response to allergic bronchopulmonary aspergillosis, wherever to boot there are airway flora organization ANd an IgG-mediated immunologic response resulting in bronchiectasis and pathology. Chronic respiratory organ aspergillosis describes syndromes with variable degrees of flora invasion and respiratory organ destruction. [2]

A Novel Eosinophilia Diagnostics Using Label‐Free Impedimetric Aptasensor for Soluble Interleukin‐5 Receptor Alpha

Recently, interleukin‐5 receptor alpha (IL‐5RA) was reported to be a key surface molecule in the regulation of eosinophil proliferation. during this study, a highly sensitive aptamer for IL‐5RA was applied to an electrochemical biosensor. The rod‐shaped gold electrodes with circular gold surface were used. The aptasensor specifically detected membrane‐bound IL‐5RA on human eosinophils according to the number of the eosinophils. We further examined the usability of soluble IL‐5RA (sIL‐5RA) in the serum as a novel biomarker for the diagnosis of eosinophil‐related diseases. once leucocyte inflammation happens, the concentration of sIL‐5RA in the blood is highly elevated. [3]

Trimethoprim‐sulfamethoxazole‐induced drug reaction with eosinophilia and systemic symptoms in a child with the congenital renal disease

We present a special case of an 8‐year‐old girl diagnosed with severe drug reaction with eosinophilia and systemic symptoms due to trimethoprim‐sulfamethoxazole for urinary tract infection prophylaxis for congenital vesicoureteral reflux. The patient is believed to own developed drug reaction with symptom and general symptoms attributable to her underlying excretory organ sickness. [4]

Pediatric Duodenal Mucosal Biopsies with Eosinophilic Infiltrates: A Clinicopathologic Study

Aims: to explain the clinicopathologic options of kids with small intestine leukocyte infiltrates (DEI).

Study Design: Retrospective.

Place and period of Study: medicine Division, Lone-Star State Children’s Hospital over twenty-four months (Jan one, 1998 –Dec thirty-one, 1999).

Methodology: youngsters with DEI at Lone-Star State Children’s Hospital over twenty-four months were known. Clinical symptomatology was analyzed by a retrospective anamnesis review. 2 medicine pathologists re-evaluated all biopsies. Follow-up was done by contacting the patients 12-36 months when the initial diagnosing. [5]

Reference

[1] Adults with eosinophilic esophagitis should consider a diet change

Date: July 18, 2014, Source: American Gastroenterological Association (web link)

[2] Lung Diseases Caused by Aspergillus and Pulmonary Eosinophilia

Hart SP. Lung Diseases Caused by Aspergillus and Pulmonary Eosinophilia. foundations of Respiratory Medicine 2018 (pp. 229-237). Springer, Cham. (web link)

[3] A Novel Eosinophilia Diagnostics Using Label‐Free Impedimetric Aptasensor for Soluble Interleukin‐5 Receptor Alpha

Youn H, Her J, Mok J, Kil B, Kim E, Park H, Ban C. A Novel Eosinophilia Diagnostics Using Label‐Free Impedimetric Aptasensor for Soluble Interleukin‐5 Receptor Alpha. Electroanalysis. (web link)

[4] Trimethoprim‐sulfamethoxazole‐induced drug reaction with eosinophilia and systemic symptoms in a child with the congenital renal disease

Maarouf M, Wickenheiser M, Krase JM, Wolter S, Shi VY. Trimethoprim‐sulfamethoxazole‐induced drug reaction with eosinophilia and systemic symptoms in a child with the congenital renal disease. Pediatric Dermatology. 2018 Sep 6. (web link)

[5] Pediatric Duodenal Mucosal Biopsies with Eosinophilic Infiltrates: A Clinicopathologic Study

  1. S. Miqdady1*, L. A. Darrisaw2, S. H. Abrams3, W. J. Klish3, M. Finegold3, and M. A. Gilger3

1Sheikh Khalifa Medical City, Abu Dhabi, P.O. Box 51900, United Arab Emirate.

2Georgia Bureau of Investigation. Decatur, Georgia 30034, USA.

3Baylor College of Medicine. Houston, Texas 77030, USA. (web link)

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