Tag: 3-diketone

The present study seeks to investigate the synthesis and structural characteristics of derivatives of Indanone, Tetralone and Naphthone. Via Claisen condensations, arylhydrazine condensations, BakerVenkataraman rearrangements, Claisen-Schmidt reactions, selective fluorinations and trifluoroacetylations in yields ranging from 22-92 percent, indanone, tetralone and naphthone derivatives and fused-ring heterocycles were prepared. Regiochemistry and stereochemistry observed in these products and their usefulness as scaffolds for the preparation of heterocyclic derivatives are of particular interest. Unusual changes such as a novel one-pot, dual trifluoroacetylation, trifluoroacetylnaphthone synthesis … Continue reading “Synthesis and Structural Features of Indanone, Tetralone and Naphthone Derivatives: Selective Fluorination and Condensation Products”