Risk of Acoustic Trauma Associated With Artillery Weapon Gunners

Posted on June 11, 2021Categories Medicine and MedicalTags , ,   Leave a comment on Risk of Acoustic Trauma Associated With Artillery Weapon Gunners

The military is a high-risk occupational deafness environment. Acoustic trauma is a sensorineural hearing disorder caused by impulsive loud noise in the 2-6 kHz range. The purpose of this research is to determine the occurrence of acoustic trauma in a Howitzer 105 gunner. The Indonesian military does not currently have a hearing conservation program. The work environment of the armed forces puts military personnel at risk of occupational hearing loss caused by the use of primary defense equipment as one … Continue reading “Risk of Acoustic Trauma Associated With Artillery Weapon Gunners”

Effect of Orally Ebselen (SPI-1005) towards Glutathione and Malondialdehyde Blood Level and Otoacoustic Emissions Result in Soldiers with Acoustic Trauma Risk

Posted on June 2, 2021Categories PharmaceuticalTags , , , ,   Leave a comment on Effect of Orally Ebselen (SPI-1005) towards Glutathione and Malondialdehyde Blood Level and Otoacoustic Emissions Result in Soldiers with Acoustic Trauma Risk

Excessive noise exposure can cause acoustic trauma to the inner ear structure (cochlea) by creating mechanical and metabolic (oxidative) stress (TA). Oxidative stress, which is induced by an increase in free radical ROS/RNS in the organs of Corti, causes apoptosis and necrosis of cochlear hair cells. Increased malondialdehyde (MDA), decreased glutathione peroxidase (GPx) enzyme, and aberrant otoacoustic emission value were all signs of oxidative stress (refer). Endogenous antioxidant enyzme (superoxide dismutase/SOD, catalase/CAT, and GPx) mediated the defence mechanism against oxidative … Continue reading “Effect of Orally Ebselen (SPI-1005) towards Glutathione and Malondialdehyde Blood Level and Otoacoustic Emissions Result in Soldiers with Acoustic Trauma Risk”