Biochemical and Molecular Pathogenetic Mechanisms behind Causation of Parkinson’s Disease

Posted on July 27, 2020Categories medical scienceTags , , , , , , , , , , , , , , , , , ,   Leave a comment on Biochemical and Molecular Pathogenetic Mechanisms behind Causation of Parkinson’s Disease

Parkinson’s disease (PD) is an age-related neurodegenerative disorder that affects approximately 1 million persons in the United States. It is characterized by resting tremor, rigidity, bradykinesia, gait disturbance and postural instability. Its pathological features include degeneration of dopaminergic neurons in the substantia nigra pars compacta coupled with intracytoplasmic inclusions known as Lewy bodies. Neurodegeneration and Lewy bodies can also be found in locus ceruleus, nucleus basalis, hypothalamus, cerebral cortex, cranial nerve motor nuclei, and central & peripheral components of autonomic … Continue reading “Biochemical and Molecular Pathogenetic Mechanisms behind Causation of Parkinson’s Disease”