Background: Arsenic is a toxicological threat in the environment today since it has been shown to be a human genotoxin and carcinogen. Aim : The aim of this study was to determine…
Tag: apoptosis
Influence of Berberine on Megakaryocyte and Apoptotic Cell Populations in Erosive Arthritis
Berberine (BB) is a protoberberine alkaloid that has a broad range of pharmacological activities and is a Janus kinase (Jak)2/3 inhibitor. However, the mechanisms of berberine’s anti-inflammatory effects on joints are still…
Assessment of the Cytotoxicity, Cell Cycle Arrest and Pro-apoptotic Effects of Two African Botanicals, Lantana ukambensis (Vatke) Verdc and Balanites aegyptiaca (L.) Delile on Human Colorectal Cancer Cells
In African traditional medicine, the plants Lantana ukambensis (Vatke) Verdc. (Verbenaceae) and Balanites aegyptiaca (L.) Delile (Zygophyllaceae) are used to treat wounds and inflammatory diseases. The aim of this study is to…
Induction of Apoptosis Pathways in Human Cervical Carcinoma Cells by Ionizing Radiation
More than half of the cancer patients undergoing radiotherapy have received radiotherapy during the course of care, and it is the most common advanced-stage treatment for cervical cancer. The goal of this…
Saussurea costus: A Source of Anticancer Bioactives
Cancer is the world’s second largest cause of death and is responsible for an estimated 9.6 million fatalities in 2018. Plant-derived products or extracts are used to treat various illnesses or diseases…
A Critical Review on Effects of Metosartan on Testes Tissue
Metosartan induces so many deleterious effects in male Wistar rats treated with drug and RNase. It causes pre maturation of sperms and reduces the sperm count as well as reduces viable sperm…
Recent Research in LNCaP Cells Inhibition of BCL-2 by Antisense Oligonucleotides Results in Compensatory Changes Involving Apoptosis,Transcription and Immunoregulation
Antisense oligonucleotides (oligos) have been evaluated for treating prostate cancer in both in vivo and in vitro models. This study evaluates the growth inhibition of in vitro propagating LNCaP cells employing mono-…
Biochemical and Molecular Pathogenetic Mechanisms behind Causation of Parkinson’s Disease
Parkinson’s disease (PD) is an age-related neurodegenerative disorder that affects approximately 1 million persons in the United States. It is characterized by resting tremor, rigidity, bradykinesia, gait disturbance and postural instability. Its…