Tag: augmentation

A large proportion of patients with treatment-resistant schizophrenia continue to have persistent symptoms and psychosocial impairment despite adequate treatment with clozapine. This group of patients with clozapine resistant schizophrenia (CRS) constitutes about 40%-70% of those with treatment-resistant schizophrenia. These patients represent the most severely ill among those with schizophrenia with higher levels of symptom severity and disability, and greater socioeconomic burden. A large body of evidence has shown that when clozapine fails, augmentation of its response with antipsychotics or other … Continue reading “The Role of Adjunctive Psychosocial Interventions in Augmenting Clozapine Response in Patients with Clozapine Resistant Schizophrenia: A Review and Illustrative Patient Histories”