Critical Overview: Ocular Angiogenesis

Posted on August 25, 2020Categories MedicineTags , , , ,   Leave a comment on Critical Overview: Ocular Angiogenesis

Angiogenesis is the formation of new blood vessels from preexisting vasculature, being mediated and regulated by a complex composed of growth factors, cytokines, cell signaling molecules and extracellular matrix components. The most important pro-angiogenesis regulator molecules are vascular endothelial factor (VEGF), fibroblasts growth factors (FGFs), hypoxia-inducible factor 1 (HIF- 1), platelet-derived growth factor (PDGF) and angiopoietins (Ang). Ocular angiogenesis can occur in retina, choroid, and cornea of the eye, leading to severe visual impairment, being related to a broad spectrum … Continue reading “Critical Overview: Ocular Angiogenesis”