Genital Self-mutilation in Schizophrenia-A Case Series

Background: In mental illness, major self-mutilation of various body parts, with or without suicidal intent, is common. It requires care since it poses a significant risk of major disability. The majority of cases…

An Autopsy Case of Disorganized Type of Schizophrenia: Dopamine Neurons in the Ventral Tegmental Area

The pathophysiology of schizophrenia has been linked to the mesolimbic dopamine (DA) system. Using tyrosine hydroxylase (TH) immunohistochemistry, we show DA-containing neuronal structures in the ventral tegmental area (VTA) of an autopsy case…

Two Clinical Cases with Paranoid-hallucinatory State: Explained by “D-cell Hypothesis” of Mental Illnesses

The “D-cell hypothesis,” which was derived from post-mortem brain studies on schizophrenia patients, demonstrates the biochemical and cellular aetiology of the paranoid-hallucinatory state. Two psychotic examples are shown to support the “D-cell hypothesis”…

Lectin-positive Spherical Deposits (SPD) in Molecular Layer of Hippocampal Dentate Gyrus of Dementia, Down’s Syndrome, and Schizophrenia: Mini Review

Lectins are proteins that bind (or crosslink) carbohydrates in a specific way. Recent research has revealed the role of glycosylation in disease aetiology. In dementia, Down’s syndrome, and schizophrenia, we found lectin-positive spherical…

A Cross-sectional Study of Dermatoglyphics Patterns in Female Schizophrenics

The goal of this study was to compare the fingerprint and palm print patterns of female schizophrenia patients to those of healthy people. The study was conducted in a cross-sectional manner. Material and…

Metrological Research of Methods and Means of EEG Analysis in Science and Medicine

This small monograph contains in-depth critical examinations on four EEG analysis methods: 1) the disadvantages and errors of coherent analysis; 2) errors in spectral estimates of EEG amplitude compared to direct amplitude measurements;…

Understanding Serotonergic Regulation of Inhibition in Cortical Activity (U-SRICA)

Our suggestion focuses on determining the causal role of serotonin (5-HT) in controlling inhibition in cortical activity and its implications for working memory maintenance. 5-HT controls inhibition in the prefrontal cortex (PFC) via…